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Index > Protein center > CXCL2(Gene name) > Human
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  • CXCL2 (Gene name),
  • C-X-C motif chemokine 2 (Protein name ),  CXCL2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CXCL2(GRO2;GROB;MIP2A;SCYB2);
    Protein name:
    C-X-C motif chemokine 2;
    Alternative:
    Macrophage inflammatory protein 2-alpha(MIP2-alpha);Growth-regulated protein beta(Gro-beta);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    107
    Sequence:
    50:
    MARATLSAAP | SNPRLLRVAL | LLLLLVAASR | RAAGAPLATE | LRCQCLQTLQ | 
    100:
    GIHLKNIQSV | KVKSPGPHCA | QTEVIATLKN | GQKACLNPAS | PMVKKIIEKM | 
    107:
    LKNGKSN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    UniGene:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-X-C motif chemokine 2
    Cat.:
    E0094h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human C-X-C motif chemokine 2
    Cat.:
    E0094m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human C-X-C motif chemokine 2
    Cat.:
    E0094r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-X-C motif chemokine 2
    Cat.:
    U0094r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-X-C motif chemokine 2
    Cat.:
    U0094m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-X-C motif chemokine 2
    Cat.:
    U0094h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human C-X-C motif chemokine 2
    Cat.:
    P0094Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-X-C motif chemokine 2
    Cat.:
    P0094Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-X-C motif chemokine 2
    Cat.:
    P0094Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-X-C motif chemokine 2
    Monoclonal Antibody for Human C-X-C motif chemokine 2
    Monoclonal Antibody for Human C-X-C motif chemokine 2
    Protein for Human C-X-C motif chemokine 2
    Protein for Human C-X-C motif chemokine 2
    Protein for Human C-X-C motif chemokine 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues."
      Tekamp-Olson P. , Gallegos C. , Bauer D. , McClain J. , Sherry B. , Fabre M. , van Deventer S. , Cerami A.
      J. Exp. Med.172:911-919(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Histiocytic lymphoma.
    2. 2.
      "Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue."
      Iida N. , Grotendorst G.R.
      Mol. Cell. Biol.10:5596-5599(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Identification of three related human GRO genes encoding cytokine functions."
      Haskill S. , Peace A. , Morris J. , Sporn S.A. , Anisowicz A. , Lee S.W. , Smith T. , Martin G. , Ralph P. , Sager R.
      Proc. Natl. Acad. Sci. U.S.A.87:7732-7736(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Eye.
    7. 7.
      Jang J.S. , Kim B.E.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 35-107
    8. 8.
      "Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair."
      Sporn S.A. , Eierman D.F. , Johnson C.E. , Morris J. , Martin G. , Ladner M. , Haskill S.
      J. Immunol.144:4434-4441(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 56-107
    9. 9.
      "Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities."
      King A.G. , Johanson K. , Frey C.L. , DeMarsh P.L. , White J.R. , McDevitt P. , McNulty D. , Balcarek J. , Jonak Z.L. , Bhatnagar P.K. , Pelus L.M.
      J. Immunol.164:3774-3782(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 39-56;IDENTIFICATION OF GRO-BETA(5-73) BY MASS SPECTROMETRY;PROTEOLYTIC PROCESSING OF N-TERMINUS;FUNCTION
    10. 10.
      "Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8."
      Qian Y.Q. , Johanson K.O. , McDevitt P.
      J. Mol. Biol.294:1065-1072(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 39-107
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